Publications and Presentations


Public Health Surveillance

Nielsen V, Song G, Rocchio C, Zambarano B, Klompas M, Chen T. Electronic Health Records Versus Survey Small Area Estimates for Public Health Surveillance. American Journal of Preventative Medicine; 04 March 2024. doi: 10.1016/j.amepre.2024.02.018. Abstract.

Cocoros NM, Willis SJ, Eberhardt K, Morrison M, Randall LM, DeMaria A, Brown CM, Madoff LC, Zambarano B, Sljivo S, Nagavedu K, Klompas M. Syndromic Surveillance for COVID-19, Massachusetts, February 2020–November 2022: The Impact of Fever and Severity on Algorithm Performance. Public Health Reports; 2023;0(0). doi:10.1177/00333549231186574. Article.

Hohman K, Martinez A, Klompas M, Kraus E, Li W, Carton T, Cocoros N, Jackson S, Karras B, Wiltz J, Wall H. Leveraging Electronic Health Record Data for Timely Chronic Disease Surveillance: The Multi-State EHR-Based Network for Disease Surveillance. Journal of Public Health Management and Practice; 29(2); p.162-173, March/April 2023. doi: 10.1097/PHH.0000000000001693. Article.

Chen T, Li W, Zambarano B, Klompas M. Small-area estimation for public health surveillance using electronic health record data: reducing the impact of underrepresentation. BMC Public Health; 09 August 2022. doi: 10.1186/s12889-022-13809-2. Article.

Canfell O, Davidson K, Woods L, Sullivan C, Cocoros NM, Klompas M, Zambarano B, Eakin E, Littlewood R, Burton-Jones A. Precision Public Health for Non-communicable Diseases: An Emerging Strategic Roadmap and Multinational Use Cases. Front. Public Health; 08 April 2022. doi: 10.3389/fpubh.2022.854525. Article.

Kraus EM, Brand B, Hohman KH, Baker EL. New Directions in Public Health Surveillance: Using Electronic Health Records to Monitor Chronic Disease. J Public Health Manag Pract. 2022 Mar-Apr 01;28(2):203-206. doi: 10.1097/PHH.0000000000001501. PMID: 35100219. Article.

Cocoros NM, Kirby C, Zambarano B, Ochoa A, Eberhardt K, Rocchio C, Ursprung WS, Nielsen VM, Durham NN, Menchaca JT, Josephson M, Erani D, Hafer E, Weiss M, Herrick B, Callahan M, Isaac T, and Klompas M. RiskScape: a data visualization and aggregation platform for public health surveillance using routine electronic health record data. Am J Public Health. Published online ahead of print December 22, 2020: e1–e8. Abstract.

Willis SJ, Cocoros NM, Randall LM, Ochoa AM, Haney G, Hsu KK, DeMaria A, Klompas M. Electronic Health Record Use in Public Health Infectious Disease Surveillance, USA, 2018–2019. Current Infectious Disease Reports. 2019;21(10):32. PubMed.

Cocoros NM, Ochoa A, Eberhardt K, Zambarano B, Klompas M. Denominators Matter: Understanding Medical Encounter Frequency and Its Impact on Surveillance Estimates Using EHR Data. eGEMs (Generating Evidence & Methods to improve patient outcomes). 2019; 7(1):31, pp. 1–6. Article.

Klompas M, Cocoros N, Menchaca JT, Erani D, Hafer E, Herrick B, Josephson M, Lee M, Weiss M, Zambarano B, Eberhardt K, Malenfant J, Nasuti L, Land T. State and local chronic disease surveillance using electronic health record systems. American Journal of Public Health 107, no. 9 (September 1, 2017): pp. 1406-1412. Abstract.

Birkhead GS, Klompas M, Shah NR. Uses of electronic health records for public health surveillance to advance public health. Annual Review of Public Health. 2015 Mar 18;36:345-59. doi: 10.1146/annurev-publhealth-031914-122747. Epub 2015 Jan 2. PubMed.

Baker MA, Kaelber DC, Bar-Shain DS, Moro PL, Zambarano B, Mazza M, Garcia C, Henry A, Platt R, Klompas M. Advanced Clinical Decision Support for Vaccine Adverse Event Detection and Reporting. Clinical Infectious Diseases. 2015;61(6):864-870. PubMed.

Vogel J, Brown JS, Land T, Platt R, Klompas M. MDPHnet: Secure, distributed sharing of electronic health record data for public health surveillance, evaluation, and planning. American Journal of Public Health 2014;104(12):2265-70. PubMed. 

Klompas M, Lazarus R, McVetta J, Eggleston M, Haney G, Kruskal B, Yih WK, Daly P, Oppedisano P, Beagan B, Lee M, Kirby C, Heisey-Grove D, DeMaria A, Platt R. Integrating clinical practice and public health surveillance using electronic medical record systems. American Journal of Preventive Medicine 2012;42:S154-162 and American Journal of Public Health 2012;102:S325-S332 (joint publication). PubMed.

Lazarus R, Klompas M, Campion FX, McNabb SN, Hou X, Daniel J, Haney G, DeMaria A, Lenert L, Platt R. Electronic Support for Public Health: Validated case finding and reporting for notifiable diseases using electronic medical data.  Journal of the American Medical Informatics Association. 2009;16:18-24. PubMed.

Klompas M, Lazarus R, Platt R, Hou X, Campion FX, Kruskal B, Haney G, Dumas W, Daniel J, DeMaria A, McNabb SJN. Automated Detection and Reporting of Notifiable Diseases Using Electronic Medical Records Versus Passive Surveillance — Massachusetts, June 2006—July 2007. MMWR Morbidity and Mortality Weekly Report 2008;57:373-6. Report link.

Infectious & Chronic Diseases

Cocoros NM, Eberhardt K, Nguyen V-T, Brown CM, DeMaria A, Madoff LC, et al. Electronic health record–based algorithm for monitoring respiratory virus–like illness. Emerg Infect Dis. 2024 Jun. Abstract.

Nguyen VT, Nagavedu K, Morrison M, Chen T, Randall LM, Landazabal C, John B, Klompas M, Cocoros NM. COVID-19 Severity in People with HIV Compared to Those Without HIV. JAIDS Journal of Acquired Immune Deficiency Syndromes:10.1097/QAI.0000000000003378, January 15, 2024. | DOI: 10.1097/QAI.0000000000003378. Abstract.

Willis SJ, Cocoros NM, Callahan M, Herrick B, Brown CM, Kruskal BA, Klompas M. Assessment of Antibiotic Prescriptions for Lyme Disease After Modification of Reporting Language for Positive Screening Test Results. JAMA Netw Open. 2022 Jan 4;5(1):e2144928. doi: 10.1001/jamanetworkopen.2021.44928. PMID: 35076704. Article.

Willis SJ, Elder H, Cocoros NM, Callahan M, Hsu KK, Klompas M. Impact of an Electronic Medical Record Best Practice Alert on Expedited Partner Therapy for Chlamydia Infection and Reinfection. Open Forum Infect Dis. 2021 Nov 16;9(1):ofab574. doi: 10.1093/ofid/ofab574. PMID: 35024371; PMCID: PMC8743117. Article.

Elder HR, Gruber S, Willis SJ, Cocoros N, Callahan M, Flagg EW, Klompas M, Hsu KK. Can Machine Learning Help Identify Patients at Risk for Recurrent Sexually Transmitted Infections? Sex Transm Dis. 2021 Jan;48(1):56-62. doi: 10.1097/OLQ.0000000000001264. PMID: 32810028. Abstract.

Willis SJ, Elder H, Cocoros N, Young J, Marcus JL, Eberhardt K, Callahan M, Herrick B, Weiss M, Hafer E, Erani D, Josephson M, Llata E, Flagg EW, Hsu KK, Klompas M. More Screening or More Disease? Gonorrhea Testing and Positivity Patterns Among Men in 3 Large Clinical Practices in Massachusetts, 2010-2017. Clin Infect Dis. 2020 Dec 3;71(9):e399-e405. doi: 10.1093/cid/ciaa066. PMID: 31967644; PMCID: PMC7904080. PubMed.

Gruber S, Krakower D, Menchaca JT, Hsu K, Hawrusik R, Maro JC, Cocoros NM, Kruskal BA, Wilson IB, Mayer KH, Klompas M. Using electronic health records to identify candidates for human immunodeficiency virus pre-exposure prophylaxis: An application of super learning to risk prediction when the outcome is rare. Stat Med. 2020 Oct 15;39(23):3059-3073. doi: 10.1002/sim.8591. Epub 2020 Jun 24. PMID: 32578905; PMCID: PMC7646998. PubMed.

Krakower DS, Gruber S, Hsu K, Menchaca JT, Maro JC, Kruskal BA, Wilson IB, Mayer KH, Klompas M. Development and validation of an automated HIV prediction algorithm to identify candidates for pre-exposure prophylaxis: a modelling study. Lancet HIV. 2019 Oct;6(10):e696-e704. doi: 10.1016/S2352-3018(19)30139-0. Epub 2019 Jul 5. PMID: 31285182; PMCID: PMC7522919. Abstract.

Dee EC, Hsu KK, Kruskal BA, Menchaca JT, Zambarano B, Cocoros N, Herrick B, Weiss MDP, Hafer E, Erani D, Josephson M, Young J, Torrone EA, Flagg EW, Klompas M. Temporal Patterns in Chlamydia Repeat Testing in Massachusetts. American Journal of Preventive Medicine. 2019;56(3):458-463. PubMed.

Yih WK, Cocoros NM, Crockett M, Klompas M, Kruskal BA, Kulldorff M, Lazarus R, Madoff LC, Morrison MJ, Smole S, Platt R.  Automated influenza-like illness reporting, an efficient adjunct to traditional sentinel surveillance.  Public Health Reports 2014;129:55-63. PubMed.

Klompas M, Eggleston E, McVetta J, Lazarus R, Li L, Platt R. Automated detection and classification of type 1 versus type 2 diabetes using electronic health record data.  Diabetes Care 2013;36:914-921. PubMed.

Allen-Dicker J, Klompas M. Comparison of electronic laboratory reports, administrative claims, and electronic health record data for acute viral hepatitis surveillance.  Journal of Public Health Practice and Management 2012;18:209-214. PubMed.

Calderwood MS, Platt R, Hou X, Malenfant J, Haney G, Kruskal B, Lazarus R, Klompas M. Real-time surveillance for tuberculosis using electronic health record data from an ambulatory practice in eastern Massachusetts.  Public Health Reports 2010; 125:843-850. PubMed.

Klompas M, Haney G, Church D, Lazarus R, Hou X, Platt R. Automated identification of acute hepatitis B using electronic medical record data to facilitate public health surveillance. PLoS One. 2008 Jul 9;3(7):e2626. PMC.


Recent Presentations

Impact of an electronic medical record best practice alert on expedited partner therapy for chlamydia infection and reinfection.
Sarah J. Willis, PhD, MPH
Council for State and Territorial Epidemiologists Annual Conference, Raleigh, NC. June 2019.

Gonorrhea Testing Patterns Among Males in Three Large Clinical Practices in Massachusetts, 2010-2017
Elizabeth C. Dee, MPH; Sarah Willis, PhD, MPH; Katherine K. Hsu, MD, MPH; Heather Elder, PhD, MPH; Noelle M. Cocoros, DSc, MPH; Jessica Young, PhD; Julia Marcus, PhD, MPH; Elizabeth A. Torrone, PhD, MSPH; Eloisa Llata, MD, MPH; Elaine W. Flagg, PhD, MS; Michael Klompas, MD, MPH
National STD Prevention Conference, Washington, DC. August 2018.

Denominators matter: Understanding medical encounter frequency and its impact on surveillance estimates using EMR data
Noelle M. Cocoros, DSc, MPH; Aileen Ochoa, MPH; Karen Eberhardt, BS; Bob Zambarano, PhD; Michael Klompas, MD
Council of State and Territorial Epidemiologists Annual Conference, West Palm Beach, FL. June 2018.

Temporal Patterns in Chlamydia Repeat Testing and Positivity Rates in Massachusetts
Elizabeth C. Dee, MPH; Katherine K. Hsu, MD, MPH; Benjamin A.Kruskal MD, PhD; John T. Menchaca, BA; Bob Zambarano, PhD; Noelle Cocoro, DSc, MPH, Brian Herrick, MD; Michelle D. Payne Weiss, MPH; Ellen Hafer, MTS, MBA; Diana Erani, MBA; Mark Josephson, Jessica Young, PhD; Michael Klompas, MD, MPH
International Society for Disease Surveillance Annual Conference, Orlando, FL. January 2018.

Automated Public Health Surveillance Using Electronic Health Record Data
Michael Klompas, MD, MPH
National Institutes of Health Collaboratory Grand Rounds. October 20, 2017

Implementing an EHR-based Distributed Data Network for Public Health Surveillance of Notifiable Diseases and Chronic Conditions: A How-To Guide with Lessons Learned from Massachusetts.
Noelle M. Cocoros, DSc, MPH; Bob Zambarano, PhD; Michael Klompas, MD, MPH
Council of State and Territorial Epidemiologists Annual Conference, Boise, ID. June 2017.

A framework for automated continuum of care reporting of selected notifiable diseases using electronic medical record data: Preliminary data for HIV in Massachusetts.
Elizabeth C. Dee, MPH; Noelle Cocoros, DSc MPH; Liisa M. Randall, PhD; Hannah Rettler, MPH; Mark Josephson; Michael Klompas, MD, MPH
Council of State and Territorial Epidemiologists Annual Conference, Boise, ID. June 2017.

Electronic Health Records, STD Surveillance, and Rapid Action
Michael Klompas, MD, MPH
2017 Clinical Trials Group Technical Consultation. May 2017.